Accelerated DNAzyme-based fluorescent nanoprobe for highly sensitive microRNA detection in live cells

Yanan Wu, Hong‐Min Meng, Juan Chen, Kemei Jiang, Ran Yang, Yingying Li, Ke Zhang, Lingbo Qu, Xiaobing Zhang, Zhaohui Li

Chemical Communications · 2019 · 40 citations · 31 references

Abstract

By assembling DNAzyme on DNA nanowires through DNA hybridization, we have developed a novel accelerated DNAzyme-based fluorescent nanoprobe for fast, sensitive and selective detection of miRNA. Moreover, the strategy was successfully applied for in situ imaging of miRNA-21 in different cell lines.

References

31