LncRNA MALAT1 inhibits osteogenic differentiation of mesenchymal stem cells in osteoporosis rats through MAPK signaling pathway. - Concepedia

Concepedia

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LncRNA MALAT1 inhibits osteogenic differentiation of mesenchymal stem cells in osteoporosis rats through MAPK signaling pathway.

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2019

Year

Shuang Zheng, Wang Yb, Ya‐Ling Yang, BP Chen, Wang Cx, Li Rh, Dongyang Huang

Abstract

LncRNA MALAT1 was lowly expressed in OP rats. Moreover, it inhibited osteogenic differentiation of BMSCs by enhancing the activation of the MAPK signaling pathway, thereby promoting OP progression.