Antibiotic Resistance Profile of Gram Positive Bacteria Isolated from Wound Infections in Minna, Bida, Kontagora and Suleja Area of Niger State

Abstract

Antibiotics resistance profiles of gram positive bacteria isolated from wound infections in four (4) General Hospitals (Bida, Kontagora, Minna and Suleja) in Niger State was carried out. Organisms isolated from surgical wounds were <i>Staphylococcus aureus</i> and <i>Streptococcus pyogenes</i>. Five hundred (500) samples (i.e. Two hundred (200) samples in Minna, One hundred (100) samples each from Suleja, Kontagora and Bida) of wound exudates from surgical wounds sites were analysed for their resistance pattern. From the five hundred (500) samples collected from all the locations, one hundred and twenty one samples (121) had <i>Strept. pyogenes</i>, one hundred and ninety seven (197) samples had <i>S. aureus. S. aureus</i> was more frequently isolated (62%) than <i>Strept. pyogenes</i> (38%) from wounds in all the locations. Both bacteria were tested for sensitivity to Tarivid, Pefloxacin, Ciprofloxacin, Augmentin, Gentamycin, Streptomycin, Ceporex, Nalidixic acid, Septrin, Ampicillin, ampiclox 30µg, zinacef 20µg, Amoxacillin, rocephin and erythromycin. Of the five hundred (500) wound samples from various locations 318 (64%) yielded growths while 182 samples (36%) yielded no growths. Most of all the isolates were sensitive to ciprofloxacin, pefloxacin and Tarivid while others were resistant to remaining antibiotics. <i>S. aureus</i> showed a higher resistance profile to most antibiotics used than <i>Strept. pyogenes.</i>