MicroRNA-214 targets COX-2 to antagonize indoxyl sulfate (IS)-induced endothelial cell apoptosis

Cardiovascular disease in chronic kidney disease. A clinical update from Kidney Disease: Improving Global Outcomes (KDIGO)

Charles A. Herzog, Richard Asinger, Alan K. Berger et al. · Kidney International · 2011 · 925 citations

Medicine, Cardiology, Nephrology +17

Cardiovascular disease and mortality in a community-based cohort with mild renal insufficiency

Bruce F. Culleton, Martin G. Larson, Peter W.F. Wilson et al. · Kidney International · 1999 · 841 citations

Medicine, Nephrology, Preventive Cardiology +15

NS-398, a new anti-inflammatory agent, selectively inhibits prostaglandin G/H synthase/cyclooxygenase (COX-2) activity in vitro

Nobuko Futaki, Satoru Takahashi, Motofumi Yokoyama et al. · Prostaglandins · 1994 · 833 citations

Medicine, Medicinal Chemistry, Pharmacology +14

Increased prevalence of oxidant stress and inflammation in patients with moderate to severe chronic kidney disease

Bengt ÖBerg, Elizabeth McMenamin, F. Lee Lucas et al. · Kidney International · 2004 · 779 citations · Full text

Medicine, Nephrology, Inflammation +13

Endothelial cells require miR-214 to secrete exosomes that suppress senescence and induce angiogenesis in human and mouse endothelial cells

Bas W. M. van Balkom, Olivier G. de Jong, Michiel Smits et al. · Blood · 2013 · 513 citations

Life Sciences, Cell Biology, Molecular Biology +14