Green Chemistry · 2019 · 76 citations · 83 references
Natural SciencesChemical EngineeringChemistryCatalysisGreen ChemistryOrganic ChemistryCatalyst PreparationHeterocyclic ChemistryOrganic SynthesisSolvent-free SynthesisMulticomponent Reaction ChemistryPyrrole ChemistryPyrrole SynthesisSolvent-free CatalysisSolvent-free Heterocycle SynthesisSolvent-free Processing
A practical method for the clean preparation of multisubstituted pyrroles <italic>via</italic> an iodine-catalyzed multicomponent reaction under metal- and solvent-free conditions was developed. In the gram-scale synthesis, the pyrroles can be easily collected through simple extraction.
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Concepción Jiménez‐González, Celia S. Ponder, Quirinus B. Broxterman et al. · Organic Process Research & Development · 2011 · 860 citations