Concepedia

Publication | Open Access

Characterization of two rat models of cystic fibrosis—KO and F508del CFTR—Generated by Crispr‐Cas9

DOIFull Paper Access

42

Citations

26

References

2019

Year

Elise Dréano, Juliette Simonin, Louise Galmiche, Claire Usal, Lotfi Slimani, Jérémy Sadoine, Laurent Tesson, Ignacio Anegón, Jean‐Paul Concordet, Aurélie Hatton,
Animal Models and Experimental Medicine

Abstract

The F508del rats reproduce the phenotypes observed in CFTR KO animals and represent a novel resource to advance the development of CF therapeutics.

References

YearCitations

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