Concepedia

Transition-metal-free direct C-3 cyanation of quinoxalin-2(1<i>H</i>)-ones with ammonium thiocyanate as the “CN” source

Jiayang Wang, Bin Sun, Liang Zhang, Tengwei Xu, Yuanyuan Xie, Can Jin

Organic Chemistry Frontiers · 2019 · 79 citations · 105 references

DOI

Concepts

Abstract

A practical protocol for TBHP-mediated oxidative C–H cyanation of quinoxalin-2(1<italic>H</italic>)-ones utilizing ammonium thiocyanate as the cyanide source has been developed under metal free conditions.

References

105

Cobalt‐Catalyzed CH Cyanation of Arenes and Heteroarenes

Jie Li, Lutz Ackermann · Angewandte Chemie International Edition · 2014 · 318 citations

, , +14

Metal-Free C(sp<sup>2</sup>)–H/N–H Cross-Dehydrogenative Coupling of Quinoxalinones with Aliphatic Amines under Visible-Light Photoredox Catalysis

Wei Wei, Leilei Wang, Pengli Bao et al. · Organic Letters · 2018 · 257 citations

, , +16

Rhodium-Catalyzed Directed C–H Cyanation of Arenes with <i>N-</i>Cyano-<i>N</i>-phenyl-<i>p</i>-toluenesulfonamide

Tian‐Jun Gong, Bin Xiao, Wan‐Min Cheng et al. · Journal of the American Chemical Society · 2013 · 245 citations

, , +6

Design and Synthesis of Potent and Multifunctional Aldose Reductase Inhibitors Based on Quinoxalinones

Xiangyu Qin, Xin Hao, Hui Han et al. · Journal of Medicinal Chemistry · 2015 · 244 citations · Full text

, , +16

Mild and Efficient Copper‐Catalyzed Cyanation of Aryl Iodides and Bromides

Henri‐Jean Cristau, Armelle Ouali, Jean‐Francis Spindler et al. · Chemistry - A European Journal · 2005 · 236 citations

, , +9