Phenotypic and genotypic characterization of carbapenem-resistant Acinetobacter baumannii isolates from Egypt

Abstract

The widespread detection of carbapenem-resistant <i>A. baumannii</i> (CR-AB) has become a real threat to the efficacy of treatment regimens. Among the studied cohort of CR-AB clinical isolates, <i>bla</i>_{<i>OXA-51</i>} , <i>bla</i>_{<i>OXA-23</i>} and <i>bla</i>_<i>VIM</i> were the most prevalent, followed by <i>bla</i>_<i>NDM-1</i> and <i>bla</i>_{<i>OXA-58</i>} . The genotypic detection of carbapenemases among CR-AB clinical isolates using PCR was most conclusive, followed closely by the phenotypic testing using CarbAcineto NP test.