MedicinePharmacotherapyCardiovascular PharmacotherapyClinical PharmacologyHemostasisAcute Ischemic StrokeAcute Stroke ManagementAntiplatelet TherapyAntithrombotic TherapyStrokeStroke PharmacotherapyAcute Ischemic Stroke ManagementAcute Ischemic Stroke TreatmentAntiplatelet DrugsCombination Antiplatelet TherapyPost-stroke Antithrombotic TherapySecondary Prevention After StrokeTransient Ischemic Attack PreventionTriple Antiplatelet Therapy
Aspirin is recommended for patients with acute ischemic stroke within 24 hours of symptom onset. It may be beneficial for dual antiplatelet therapy including clopidogrel and aspirin to be administered in patients with minor stroke or transient ischemic attack for early secondary prevention, however, bleeding risk remains uncertain. This article will review the published literature concerning the role of dual antiplatelet therapy for secondary stroke prevention with focus on balancing both risk and benefit.
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Hans‐Christoph Diener, Julien Bogousslavsky, Lawrence Brass et al. · The Lancet · 2004 · 2.3K citations
Clopidogrel with Aspirin in Acute Minor Stroke or Transient Ischemic Attack
Yongjun Wang, Yilong Wang, Xingquan Zhao et al. · New England Journal of Medicine · 2013 · 1.8K citations · Full text