Highly selective synthesis of 2,5-bis(aminomethyl)furan <i>via</i> catalytic amination of 5-(hydroxymethyl)furfural with NH₃ over a bifunctional catalyst

Abstract

A simple and highly efficient method was developed for one pot transformation of 5-(hydroxymethyl)furfural (5-HMF) into 2,5-bis(aminomethyl)furan (BAF) over bifunctional Cu₄Ni₁Al₄O<italic>x</italic> catalyst using two-stage reaction process, affording the BAF in 85.9% yield.