A dominant <i>RAD51C</i> pathogenic splicing variant predisposes to breast and ovarian cancer in the Newfoundland population due to founder effect - Concepedia

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Publication | Open Access

A dominant <i>RAD51C</i> pathogenic splicing variant predisposes to breast and ovarian cancer in the Newfoundland population due to founder effect

DOI Full Paper Access

11

Citations

41

References

2019

Year

Lesa Dawson, Kerri Smith, Salem Werdyani, Robyn Ndikumana, Cindy Penney, Louisa Wiede, Kendra L. Smith, Justin A. Pater, Andrée MacMillan, Jane Green,

Molecular Genetics & Genomic Medicine

Abstract

The RAD51C c.571 + 4A > G variant affects mRNA splicing and should be re-classified as pathogenic according to American College of Medical Genetics and Genomics guidelines.

References

	Year	Citations

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