Concepedia

Knockdown of lncRNA <i>PVT1</i> Inhibits Vascular Smooth Muscle Cell Apoptosis and Extracellular Matrix Disruption in a Murine Abdominal Aortic Aneurysm Model.

Zhidong Zhang, Gangqiang Zou, Xiaosan Chen, Wei Lü, Jianyang Liu, Shuiting Zhai, Gang Qiao

PubMed · 2019 · 59 citations · 31 references

DOIFull text

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Abstract

suppresses VSMC apoptosis, ECM disruption, and serum pro-inflammatory cytokines in a murine Ang II-induced AAA model.

References

31

Targeted gene disruption of matrix metalloproteinase-9 (gelatinase B) suppresses development of experimental abdominal aortic aneurysms

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Inflammation and Matrix Metalloproteinases in the Enlarging Abdominal Aortic Aneurysm

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Smooth muscle phenotypic modulation is an early event in aortic aneurysms

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Inhibition of microRNA-29b reduces murine abdominal aortic aneurysm development

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Expression of matrix metalloproteinases and their inhibitors in aneurysms and normal aorta

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, , +14