Cleaning the sleeping brain – the potential restorative function of the glymphatic system

A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid β

Jeffrey J. Iliff, Minghuan Wang, Yonghong Liao et al. · Science Translational Medicine · 2012 · 5.6K citations · Full text

Medicine, Neurobiology, Neuroscience +16

Sleep Drives Metabolite Clearance from the Adult Brain

Lulu Xie, Hongyi Kang, Qiwu Xu et al. · Science · 2013 · 5.3K citations · Full text

Life Sciences, Neurobiology, Neuroscience +15

Two-Process Model of Sleep Regulation

2008 · 4K citations

Life Sciences, Neurobiology, Neuroscience +12

Amyloid-β Dynamics Are Regulated by Orexin and the Sleep-Wake Cycle

Jae-Eun Kang, Miranda M. Lim, Randall J. Bateman et al. · Science · 2009 · 1.5K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Impairment of paravascular clearance pathways in the aging brain

Benjamin T. Kress, Jeffrey J. Iliff, Maosheng Xia et al. · Annals of Neurology · 2014 · 1.5K citations · Full text

Medicine, Neuroscience, Physiology +17