Modulation of CD39 and Exogenous APT102 Correct Immune Dysfunction in Experimental Colitis and Crohn’s Disease - Concepedia

Concepedia

Publication | Open Access

Modulation of CD39 and Exogenous APT102 Correct Immune Dysfunction in Experimental Colitis and Crohn’s Disease

DOI Full Paper Access

21

Citations

35

References

2019

Year

Rene’ J. Robles, Samiran Mukherjee, Marta Vuerich, Anyan Xie, Rasika Harshe, Peter J. Cowan, Eva Csizmadia, Yan Wu, Alan C. Moss, Ridong Chen,

Journal of Crohn s and Colitis

Abstract

hCD39 overexpression ameliorated experimental colitis and prevented hypoxia-related damage in vivo. Exogenous administration of APT102 boosted AhR-mediated regulatory effects in vivo while enhancing Treg functions in Crohn's disease in vitro.

References

	Year	Citations

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