Metal‐Free C3 Hydroxylation of Quinoxalin‐2(1<i>H</i>)‐ones in Water

Abstract

Abstract A practical protocol for the preparation of quinoxaline‐2,3(1 H ,4 H )‐diones through direct C( sp 2 )−H hydroxylation of quinoxalin‐2(1 H )‐ones in recyclable DL‐α‐Tocopherol methoxypolyethylene glycol succinate solution (2 wt% in water) (TPGS‐750‐M/H 2 O) was developed. The target products were exclusively generated and could be collected through extraction and recrystallization. magnified image