Concepedia

Metal‐Free C3 Hydroxylation of Quinoxalin‐2(1<i>H</i>)‐ones in Water

Sha Peng, Die Hu, Jiali Hu, Ying‐Wu Lin, Shanshan Tang, Hai‐Shan Tang, Junyi He, Zhong Cao, Wei‐Min He

Advanced Synthesis & Catalysis · 2019 · 55 citations · 81 references

DOI

Concepts

Abstract

Abstract A practical protocol for the preparation of quinoxaline‐2,3(1 H ,4 H )‐diones through direct C( sp 2 )−H hydroxylation of quinoxalin‐2(1 H )‐ones in recyclable DL‐α‐Tocopherol methoxypolyethylene glycol succinate solution (2 wt% in water) (TPGS‐750‐M/H 2 O) was developed. The target products were exclusively generated and could be collected through extraction and recrystallization. magnified image

References

81

Metal-Free C(sp<sup>2</sup>)–H/N–H Cross-Dehydrogenative Coupling of Quinoxalinones with Aliphatic Amines under Visible-Light Photoredox Catalysis

Wei Wei, Leilei Wang, Pengli Bao et al. · Organic Letters · 2018 · 257 citations

, , +16

Direct C–H Cyanoalkylation of Quinoxalin-2(1<i>H</i>)-ones via Radical C–C Bond Cleavage

Lin Yang, Pin Gao, Xin‐Hua Duan et al. · Organic Letters · 2018 · 220 citations

, , +14

Direct phosphonation of quinoxalin-2(1H)-ones under transition-metal-free conditions

Ming Gao, Yi Li, Lijuan Xie et al. · Chemical Communications · 2016 · 215 citations

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Transition-Metal-Free Direct C–H Arylation of Quinoxalin-2(1<i>H</i>)-ones with Diaryliodonium Salts at Room Temperature

Kun Yin, Ronghua Zhang · Organic Letters · 2017 · 186 citations

, , +13

Electrochemically dehydrogenative C–H/P–H cross-coupling: effective synthesis of phosphonated quinoxalin-2(1<i>H</i>)-ones and xanthenes

Kejing Li, Yangye Jiang, Kun Xu et al. · Green Chemistry · 2019 · 183 citations

, , +12