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Evaluation of Ketanserin in the Prevention of Restenosis After Percutaneous Transluminal Coronary Angioplasty

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1993

Year

Patrick W. Serruys, Werner Klein, Jan G.P. Tijssen, Wolfgang Rutsch, Guy R. Heyndrickx, Håkan Emanuelsson, Sarah W. Ball, O. Decoster, E. Schoeder, Henry Liberman,
RePub (Erasmus University, Rotterdam)

Abstract

BACKGROUND. Ketanserin is a serotonin S2-receptor antagonist that inhibits the platelet activation and vasoconstriction induced by serotonin and also inhibits the mitogenic effect of serotonin on vascular smooth muscle cells. METHODS AND RESULTS. We conducted a randomized, double blind,