Adaptive Immune Resistance to Intravesical BCG in Non–Muscle Invasive Bladder Cancer: Implications for Prospective BCG-Unresponsive Trials - Concepedia

Concepedia

Publication | Open Access

Adaptive Immune Resistance to Intravesical BCG in Non–Muscle Invasive Bladder Cancer: Implications for Prospective BCG-Unresponsive Trials

DOI Full Paper Access

156

Citations

32

References

2019

Year

Max Kates, Andrés Matoso, Woonyoung Choi, Alexander S. Baras, Marcus J. Daniels, Kara A. Lombardo, Aaron Brant, Nina Mikkilineni, David J. McConkey, Ashish M. Kamat,

Clinical Cancer Research

Abstract

One mechanism of BCG failure may be adaptive immune resistance. Baseline tumor PD-L1 expression predicts an unfavorable response to BCG and if validated, could be used to guide therapeutic decisions.

References

	Year	Citations

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