Immunologic Disorders in Infants and Children

Abstract

and small-for-gestational age babies than in term ones,' and pronounced alterations occur in preterm infants with idiopathic respiratory distress syndrome.3 Furthermore, calculations seem to indicate a lower saturation of the binding sites of serum TBG in healthy, low birthweight infants and in preterm infants with hyaline membrane disease compared with that of term infants during the first weeks of life.3 4 6 Although the T3 uptake tests may have clinical applications in infants, the T3 tests are sometimes difficult to interpret and do not elucidate the changes in serum thyroid hormone-binding protein concentrations in healthy and sick newborn infants of various maturities.