Trial of Apremilast for Oral Ulcers in Behçet’s Syndrome

Gülen Hatemi, Alfred Mahr, Yoshiaki Ishigatsubo, Yeong-Wook Song, Mitsuhiro Takeno, Do Young ‍Kim, Melike Melikoğlu, Sue Cheng, Shannon McCue, Maria Paris,

New England Journal of Medicine · 2019 · 188 citations · 14 references

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Abstract

In patients with oral ulcers associated with Behçet's syndrome, apremilast resulted in a greater reduction in the number of oral ulcers than placebo but was associated with adverse events, including diarrhea, nausea, and headache. (Funded by Celgene; ClinicalTrials.gov number, NCT02307513.).

References

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