Personalized Medicine · 2019 · 10 citations · 30 references
MedicineCardiologyInternal MedicineClinical CardiologyInterventional CardiologyPreventive CardiologyAcute Coronary SyndromesCardiac BiomarkersCardiovascular DiseaseCoronary Artery DiseaseIschemic Heart DiseaseLipoprotein AnalysisAcute Myocardial Infarction DiagnosisAtherogenic Lipoprotein AssessmentCardiovascular Risk Stratification Using LipoproteinsCoronary Physiologic AssessmentLipoprotein(a) ElevationOperating Characteristic CurvesPositive Predictive ValueReceiver Operating Characteristic Analysis
Aim: The aim of the present study was to examine the predictive value of lipoprotein(a) (Lp[a]) levels for coronary collateral circulation (CCC) in patients with acute myocardial infarction (AMI). Method & methods: A total of 409 consecutive patients with AMI were enrolled for this study. Patients were divided into two groups according to rentrop grades assessed by coronary angiography: bad (n = 277) and good CCC group (n = 132). Result: Patients with bad CCC had a higher level of Lp(a) than that with good CCC (median Lp[a] 219.1 vs 122.0 mg/l). The area under the receiver-operating characteristic curves of Lp(a) in predicting bad CCC was 0.647 (95% CI: 0.592–0.702) with the cut-off value of 199.0 mg/l. Conclusion: Our data firstly suggested that Lp(a) might be a useful marker for CCC after AMI.
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