Antibacterial Nanoparticles with Universal Adhesion Function Based on Dopamine and Eugenol

Abstract

In this work, dopamine methacrylamide (DMA) and eugenyl methacrylate (EMA) were used to synthesize polymeric particles of Poly (DMA-co-EMA) by free radical precipitation copolymerization. These two monomers were modified from dopamine (consisting of the catechol moieties adhering to various materials) and eugenol (with antibacterial property), respectively. The proton nuclear magnetic resonance (1H NMR) and Fourier transform infrared (FT-IR) spectroscopy were applied to confirm the successful synthesis of the two monomers and copolymer. The scanning electron microscope (SEM) images showed the size and morphology of the polymer particles. The results indicated that regular particles with uniform size could be obtained with a monomer feeding ratio of 5꞉5. The results of antibacterial activity test indicated that the obtained polymer particles have an antibacterial rate over 90% to Eugenia coli.