Toll-like receptor 9 polymorphisms and <i>Helicobacter pylori</i> influence gene expression and risk of gastric carcinogenesis in the Brazilian population.

Abstract

Our findings show that TLR9 rs5743836 and rs187084 polymorphisms are associated with a higher risk of carcinogenesis gastric, and that TLR9 mRNA levels can be modulated by TLR9-1237 TC + CC variant genotypes and <i>H. pylori</i> infection.