Insulin-like growth factor 2 mRNA-binding protein 1 promotes cell proliferation <i>via</i> activation of AKT and is directly targeted by microRNA-494 in pancreatic cancer

Abstract

Our results revealed that upregulated IGF2BP1 promotes the proliferation of pancreatic cancer cells <i>via</i> the AKT signaling pathway and confirmed that the activation of IGF2BP1 is partly due to the silencing of miR-494.