Metformin regulates tight junction of intestinal epithelial cells via MLCK-MLC signaling pathway. - Concepedia

Concepedia

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Metformin regulates tight junction of intestinal epithelial cells via MLCK-MLC signaling pathway.

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References

2017

Year

Zhou Hy, Hong Zhu, Yao Xm, Qian Jp, Jin‐Young Yang, Pan Xd, Chen Xd

Abstract

Metformin can stabilize and up-regulate tight junction protein by inhibiting MLCK-MLC signaling pathway, thus ameliorating the tight junction of intestinal epithelial cells.