Concepedia

High-Grade Progression Confers Poor Survival in Pancreatic Neuroendocrine Tumors

Johan Botling, Ángela Lamarca, D. Bajic, Olov Norlén, Vincent Lönngren, Josefine Kjaer, Barbro Eriksson, Staffan Welin, Per Hellman, Guido Rindi,

Neuroendocrinology · 2019 · 61 citations · 15 references

DOI

Abstract

A longitudinal increase in Ki-67 index and increase in tumor grade were observed in a majority of PanNETs included in this study. We propose that increase in Ki-67 index and high-grade progression should be investigated further as important biomarkers in PanNET.

References

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Trends in the Incidence, Prevalence, and Survival Outcomes in Patients With Neuroendocrine Tumors in the United States

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