Pathogen-induced activation of disease-suppressive functions in the endophytic root microbiome

TLDR

Soils can suppress plant pathogen disease through plant-associated microbiota, a phenomenon observed in certain soils. The study investigates how root endophytes contribute to fungal disease suppression. Endophytic bacteria in sugar beet roots activate biosynthetic gene clusters and produce antifungal enzymes and secondary metabolites such as phenazines, polyketides, and siderophores to inhibit Rhizoctonia solani. Transcriptional analysis revealed that these endophytes activate biosynthetic pathways that suppress the wilt fungus Rhizoctonia solani. Carrión et al.

Abstract

Protecting plants from the inside out Some soils show a remarkable ability to suppress disease caused by plant pathogens, an ability that is attributed to plant-associated microbiota. Carrión et al. investigated the role of endophytes, the intimate microbial community found within roots, in fungal disease suppression (see the Perspective by Tringe). The wilt fungus Rhizoctonia solani infects sugar beets, whereupon transcriptional analysis shows that several bacterial endophyte species activate biosynthetic gene clusters to cause disease suppression. These organisms produce antifungal effectors, including enzymes that can digest fungal cell walls, and secondary metabolites, including phenazines, polyketides, and siderophores, which may contribute to the antifungal phenotype. Science , this issue p. 606 ; see also p. 568