Mosaicism for <i>KCNJ5</i> Causing Early-Onset Primary Aldosteronism due to Bilateral Adrenocortical Hyperplasia

Abstract

Thus, this patient represents a unique case of BAH due to a mosaic KCNJ5 defect. Undoubtedly, his milder PA compared with other known cases of FH-III, was due to his mosaicism. This case has a number of implications for the prognosis, treatment, and counseling of the many patients with PA due to BAH that are seen in hypertension clinics.