Visible Light Photoredox-Catalyzed α-Alkylation of Cyclic Tertiary Arylamines

Abstract

An efficient method was successfully developed to obtain cyclic β-amino ketones via visible-light photoredox catalysis. With this catalytic system, vinyl azides and <i>N</i>-Ph pyrrolidines react to form cyclic β-amino ketones by α-amino radical addition. This method provides a simple, mild, straightforward, and novel paradigm to prepare important β-amino ketones.