Concepedia

Publication | Closed Access

Enzymatic debridement: is HA-collagenase the right synergy? Randomized double-blind controlled clinical trial in venous leg ulcers.

11

Citations

0

References

2017

Year

Alessandro Scalise, Ferdinando Campitiello, Alessandro Della Corte, Pasquale Longobardi, Marilena Di Salvo, Caterina Tartaglione, Constanza Godoy Santin, Nicola Giordan, Giorgio Guarnera
PubMed

Abstract

Chronic venous ulcers treated with this novel compound of Hyaluronic Acid and collagenase resulted in a significantly higher debridement rate at Day 15 vs. the control group. Hyaluronic Acid-Collagenase was well tolerated and a low degree of pain was perceived during dressing change. The preparation of 0.2% of Hyaluronic acid-collagenase shows significant benefits in the management of chronic ulcers.