Concepedia

Curcumin Nanoparticles Enhance Mycobacterium bovis BCG Vaccine Efficacy by Modulating Host Immune Responses

Shaheer Ahmad, Debapriya Bhattacharya, Santosh K. Kar, Anand Ranganathan, Luc Van Kaer, Gobardhan Das

Infection and Immunity · 2019 · 34 citations · 40 references

DOIFull text

Open access

Concepts

Abstract

Tuberculosis (TB) is one of the deadliest diseases, causing ∼2 million deaths annually worldwide. Mycobacterium bovis bacillus Calmette-Guérin (BCG), the only TB vaccine in common use, is effective against disseminated and meningeal TB in young children but is not effective against adult pulmonary TB.

References

40

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

Estelle Bettelli, Yijun Carrier, Wenda Gao et al. · Nature · 2006 · 6.9K citations

, , +16

Efficacy of BCG Vaccine in the Prevention of Tuberculosis

Graham A. Colditz · JAMA · 1994 · 1.9K citations

, , +17

The Efficacy of Bacillus Calmette-Guerin Vaccination of Newborns and Infants in the Prevention of Tuberculosis: Meta-Analyses of the Published Literature

Graham A. Colditz, Catherine S. Berkey, Frederick Mosteller et al. · PEDIATRICS · 1995 · 692 citations

, , +17

Mesenchymal stem cells generate a CD4+CD25+Foxp3+ regulatory T cell population during the differentiation process of Th1 and Th17 cells

Patricia Luz‐Crawford, Mónica Kurte, Javiera Bravo‐Alegria et al. · Stem Cell Research & Therapy · 2013 · 501 citations · Full text

, , +17

The voltage-gated Kv1.3 K+ channel in effector memory T cells as new target for MS

Heike Wulff, Peter A. Calabresi, Rameeza Allie et al. · Journal of Clinical Investigation · 2003 · 418 citations · Full text

, , +17