Breast cancer molecular subtypes in oman: correlation with age, histology, and stage distribution - analysis of 542 cases.

Abstract

The molecular classification and sub-typing of BC have revealed ethnic and geographic variation. Luminal A subtype is the most common among Omani female breast cancers but it is less common than in Western females. BCL subtype is highest among Omani females compared with Western females. These differences may have diagnostic, therapeutic and prognostic implications. Large scale and multi-centre studies may confirm these findings and can be translated and incorporated to pertinent management strategies. Key Words: Molecular subtypes, breast cancer, Oman, Royal Hospital.