Publication | Open Access

Rare-variant pathogenicity triage and inclusion of synonymous variants improves analysis of disease associations of orphan G protein–coupled receptors

Genome-wide Association StudyAllelic VariantDisease AssociationsImmunodeficienciesPathogenesisGeneticsGenetic EpidemiologyImmunodominancePathologySynonymous VariantsDisease Gene IdentificationMedicineVariant InterpretationRare-variant Pathogenicity Triage