Concepedia

Double-blind, Placebo-controlled Trial to Evaluate the Effectiveness of <i>Polypodium Leucotomos</i> Extract in the Treatment of Melasma in Asian Skin: A Pilot Study.

Chee‐Leok Goh, Sai Yee Chuah, Steven Tien, Guan Thng, María Alejandra Vitale, Arancha Delgado-Rubin

PubMed · 2018 · 52 citations · 17 references

Concepts

Abstract

The oral PLE aqueous extract product appears to be a safe and effective adjunctive treatment for melasma in combination with topical hydroquinone and sunscreen.

References

17

Reliability assessment and validation of the Melasma Area and Severity Index (MASI) and a new modified MASI scoring method

Amit G. Pandya, Linda S. Hynan, Rafia Bhore et al. · Journal of the American Academy of Dermatology · 2010 · 327 citations · Full text

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Development and validation of a health-related quality of life instrument for women with melasma

Rajesh Balkrishnan, Amy McMichael, Fabian Camacho et al. · British Journal of Dermatology · 2003 · 289 citations

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Melasma: A clinico-epidemiological study of 312 cases

SanjayK Rathi, Arun Achar · Indian Journal of Dermatology · 2011 · 228 citations · Full text

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Oral Polypodium leucotomos extract decreases ultraviolet-induced damage of human skin

Maritza A. Middelkamp‐Hup, Madhu A. Pathak, Concepción Parrado et al. · Journal of the American Academy of Dermatology · 2004 · 169 citations

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Orally administered polypodium leucotomos extract decreases psoralen-UVA–induced phototoxicity, pigmentation, and damage of human skin

Maritza A. Middelkamp‐Hup, Madhu A. Pathak, Concepción Parrado et al. · Journal of the American Academy of Dermatology · 2003 · 137 citations

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