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ROS-dependent DNA damage contributes to crizotinib-induced hepatotoxicity via the apoptotic pathway

Crizotinib-induced HepatotoxicityHepatologyMedicineLiver PhysiologyApoptosisAutophagyHepatitisCell DeathPathologyApoptotic PathwayHepatotoxicityReactive Oxygen SpeciePharmacologyCell BiologyDrug-induced Liver InjuryToxicological MechanismOxidative Stress