Bone Mineral Density T-Scores Derived from CT Attenuation Numbers (Hounsfield Units): Clinical Utility and Correlation with Dual-energy X-ray Absorptiometry.

Abstract

Although lumbar trabecular HU T-scores are lower than DXA T-scores, thresholds can be selected to achieve high sensitivity and specificity when screening for osteoporosis. Patients with a lumbar T-score_HU ≤ -3.0 should be referred for additional evaluation. Further research into HU T-scores and clinical correlates may also provide a tool to assess changes in vertebral bone and the relationship to fracture risk across the lifespan.