Concepedia

Developmentally regulated KCC2 phosphorylation is essential for dynamic GABA-mediated inhibition and survival

Miho Watanabe, Jinwei Zhang, M. Shahid Mansuri, Jingjing Duan, Jason K. Karimy, Eric Delpire, Seth L. Alper, Richard P. Lifton, Atsuo Fukuda, Kristopher T. Kahle

Science Signaling · 2019 · 68 citations · 66 references

DOI

Concepts

Abstract

extrusion. These data identify a previously unknown phosphorylation-dependent KCC2 regulatory mechanism during CNS development that is essential for dynamic GABA-mediated inhibition and survival.

References

66

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

Jürgen Cox, Matthias Mann · Nature Biotechnology · 2008 · 15.7K citations

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Epigenetic Regulations of GABAergic Neurotransmission: Relevance for Neurological Disorders and Epigenetic Therapy

Shikshya Shrestha, Steven M. Offer · Medical Epigenetics · 2016 · 9K citations · Full text

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The Perseus computational platform for comprehensive analysis of (prote)omics data

Stefka Tyanova, Tikira Temu, Pavel Sinitcyn et al. · Nature Methods · 2016 · 8.9K citations

, , +10

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

Jürgen Cox, Nadin Neuhauser, Annette Michalski et al. · Journal of Proteome Research · 2011 · 5.9K citations · Full text

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PhosphoSitePlus, 2014: mutations, PTMs and recalibrations

Peter Hornbeck, Bin Zhang, Beth Murray et al. · Nucleic Acids Research · 2014 · 3.5K citations · Full text

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