Viable pigs after simultaneous inactivation of porcine MHC class I and three xenoreactive antigen genes GGTA1, CMAH and B4GALNT2 - Concepedia

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Viable pigs after simultaneous inactivation of porcine MHC class I and three xenoreactive antigen genes GGTA1, CMAH and B4GALNT2

DOI Full Paper Access

105

Citations

27

References

2019

Year

Konrad Fischer, Beate Rieblinger, Rabea Hein, Riccardo Sfriso, Julia Zuber, Andrea Fischer, Bernhard Klinger, Wei Liang, Krzysztof Flisikowski, Mayuko Kurome,

Xenotransplantation

Abstract

We showed that pigs carrying several xenoprotective transgenes and knockouts of xenoreactive antigens can be readily generated and these modifications will have significant effects on xenograft survival.

References

	Year	Citations

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