Concepedia

FOXO1 transcription factor regulates chondrogenic differentiation through transforming growth factor β1 signaling

Ichiro Kurakazu, Yukio Akasaki, Mitsumasa Hayashida, Hidetoshi Tsushima, Norio Goto, Takuya Sueishi, Masakazu Toya, Masanari Kuwahara, Ken Okazaki, Tomás Duffy,

Journal of Biological Chemistry · 2019 · 65 citations · 40 references

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Concepts

Abstract

during chondrogenic differentiation. These results suggest that FOXO1 is necessary for not only SOX9 expression, but also cell-cycle arrest during chondrogenic differentiation via TGFβ1 signaling.

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