MMP-2 and MMP-9 mediate cigarette smoke extract-induced epithelial-mesenchymal transition in airway epithelial cells via EGFR/Akt/GSK3β/β-catenin pathway: Amelioration by fisetin

The Structure of the β-Catenin/E-Cadherin Complex and the Molecular Basis of Diverse Ligand Recognition by β-Catenin

Andrew H. Huber, William I. Weis · Cell · 2001 · 787 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Epithelial to mesenchymal transition is increased in patients with COPD and induced by cigarette smoke

Javier Milara, Teresa Peiró, Adela Serrano et al. · Thorax · 2013 · 335 citations · Full text

Medicine, Cell Biology, Carcinogenesis +13

Differential effects of cigarette smoke on oxidative stress and proinflammatory cytokine release in primary human airway epithelial cells and in a variety of transformed alveolar epithelial cells

Aruna Kode, Se‐Ran Yang, Irfan Rahman · Respiratory Research · 2006 · 274 citations · Full text

Pharmacy, Toxicology, Immunotoxicology +15

Activation of EGFR promotes squamous carcinoma SCC10A cell migration and invasion via inducing EMT‐like phenotype change and MMP‐9‐mediated degradation of E‐cadherin

Jianhong Zuo, Wei Zhu, Maoyu Li et al. · Journal of Cellular Biochemistry · 2011 · 260 citations

Medicine, Cell Biology, Oncology +17

Fisetin, a novel dietary flavonoid, causes apoptosis and cell cycle arrest in human prostate cancer LNCaP cells

Naghma Khan, Farrukh Afaq, Deeba N. Syed et al. · Carcinogenesis · 2008 · 215 citations · Full text

Medicine, Oncology, Pharmacology +17