Altered Cytotoxicity Profile of <scp>CD</scp>8+ T Cells in Ankylosing Spondylitis

Abstract

Our findings indicate that AS patients have an altered cytotoxic T cell profile. These data suggest that CD8+ T cells with a cytotoxic phenotype are recruited to the joints, where they exhibit an activated phenotype. Thus, a central role for CD8+ T cells in AS may have been overlooked and deserves further study.