Concepedia

Publication | Open Access

TMS as a pharmacodynamic indicator of cortical activity of a novel anti‐epileptic drug, XEN1101

DOIFull Paper Access

36

Citations

33

References

2019

Year

Isabella Premoli, Pierre Gilbert Rossini, Paul Goldberg, Kristina Posadas, Louise Green, Noah Yogo, Simon N. Pimstone, Eugenio Abela, Gregory N. Beatch, Mark P. Richardson
Annals of Clinical and Translational Neurology

Abstract

Changes from baseline in TMS measures provided evidence that 20 mg of XEN1101 suppressed cortical and corticospinal excitability, consistent with the effects of other AEDs. These results support the implementation of TMS as a tool to inform early-stage clinical trials.

References

YearCitations

Page 1