High-density lipoprotein remodelled in hypercholesterolaemic blood induce epigenetically driven down-regulation of endothelial HIF-1α expression in a preclinical animal model - Concepedia

Concepedia

Publication | Open Access

High-density lipoprotein remodelled in hypercholesterolaemic blood induce epigenetically driven down-regulation of endothelial HIF-1α expression in a preclinical animal model

DOI Full Paper Access

40

Citations

35

References

2019

Year

Soumaya Ben‐Aicha, Rafael Escate, Laura Casaní, Teresa Padró, Esther Peña, Gemma Arderiu, Guiomar Mendieta, Lina Badimón, Gemma Vilahur

Cardiovascular Research

Abstract

Hypercholesterolaemia induces changes in the miRNA content of HDL enhancing miR126 and its delivery to ECs with the consequent down-regulation of its target gene HIF1α.

References

	Year	Citations

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