ChemCatChem · 2019 · 16 citations · 34 references
Natural SciencesChemistryCatalysisOrganic ChemistryCross-coupling ReactionsHeterocycle SynthesisHeterocyclic ChemistryHeterocyclic CompoundsOrganic SynthesisRadical ReactionsHeterocycle FunctionalizationRing-forming Reactions
Abstract Ni‐catalyzed radical difunctionalization of alkenes with iododifluoromethyl ketones was realized for the synthesis of α,α ‐difluoroketones. This reaction can also be used for the construction of analogs containing 5‐membered heterocycles through radical addition and sequenced cyclization reactions.
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