Site-Selective Catalytic Deaminative Alkylation of Unactivated Olefins

Abstract

A catalytic deaminative alkylation of unactivated olefins is described. The protocol is characterized by its mild conditions, wide scope, including the use of ethylene as substrate, and exquisite site-selectivity pattern for both α-olefins and internal olefins, thus unlocking a new catalytic platform to forge <i>sp</i>³-<i>sp</i>³ linkages, even in the context of late-stage functionalization.