T-Cell Receptor Stimulation Enhances the Expansion and Function of CD19 Chimeric Antigen Receptor–Expressing T Cells - Concepedia

Concepedia

Publication | Open Access

T-Cell Receptor Stimulation Enhances the Expansion and Function of CD19 Chimeric Antigen Receptor–Expressing T Cells

DOI Full Paper Access

49

Citations

31

References

2019

Year

Natalia Lapteva, Margaret Gilbert, Iulia Diaconu, Lisa Rollins, Mina Al-Sabbagh, Swati Naik, Robert A. Krance, Tamara Tripic, Manasa Hiregange, Darshana Raghavan,

Clinical Cancer Research

Abstract

Dual T-cell receptor and CAR stimulation can thus potentiate effector cell expansion and CAR-target cell killing, even when infusing low numbers of effector cells without cytoreduction.

References

	Year	Citations

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