Concepedia

Abstract

Book reviews the pial vessels, the development of brain "oedema", and changes in the intracranial and cerebral venous press- ures during acute hypertension.Dr Auer, in common with other workers, found that severe induced hypertension causes cerebral arteriolar dilation, an increase in cerebral blood flow and dysfunction of the blood-brain barrier.There is, therefore, increasing, if not conclusive, evidence that forced dila- tation and over-distension of the cere- bral resistance vessels and cerebral "oedema" formation are the pathophysiological basis of hypertensive encephalopathy.This treatise contains a useful and informative account of the past and present knowledge in this field, and summarises that clinical significance of the experimental results at the end.It is well illustrated with some coloured figures and cites most of the relevant literature.This book is highly rec- ommended to those with an interest in the microcirculation of the brain.