Profiles of Coagulation and Fibrinolysis Activation-Associated Molecular Markers of Atypical Hemolytic Uremic Syndrome in the Acute Phase

Satoko Sakurai, Hideki Kato, Yoko Yoshida, Yuka Sugawara, Madoka Fujisawa, Atsushi Yasumoto, Masanori Matsumoto, Yoshihiro Fujimura, Yutaka Yatomi, Masaomi Nangaku

Journal of Atherosclerosis and Thrombosis · 2019 · 14 citations · 29 references

DOIFull text

Open access

Abstract

We revealed the profiles and distributions of coagulation and fibrinolysis tests of aHUS and secondary TMA patients. All tests were enhanced compared to HV; however, our results showed the no specificities in distinguishing aHUS from secondary TMA patients. We also clarified that some aHUS patients fulfilled DIC diagnostic criteria, indicating that DIC itself cannot be an exclusion criterion of aHUS.

References

29