BMJ Open · 2019 · 33 citations · 18 references
Concurrent prescribing of opioids and benzodiazepine receptor modulators is common in Alberta despite the ongoing guidance of many clinical resources. Older patients, those taking higher doses of opioids, and for longer durations may be at particular risk of adverse outcomes and may be worthy of closer follow-up for assessment for dose tapering or discontinuations. As well, those with higher healthcare utilisation (seeking multiple providers) should also be closely monitored. Continued surveillance of concurrent use of these medications is warranted to ensure that safe drug use recommendations are being followed by health providers.
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Guideline for opioid therapy and chronic noncancer pain
Jason W. Busse, Samantha Craigie, David N. Juurlink et al. · Canadian Medical Association Journal · 2017 · 707 citations · Full text