European Respiratory Journal · 2019 · 103 citations · 160 references
MedicineImmunologyInternal MedicineAllergyGeneral Internal MedicineHypersensitivityAcute Asthma ExacerbationAcute Exacerbation ManagementAllergic ConditionsAsthma ManagementAsthma PharmacotherapyRespiratory AllergyAdult Asthma ExacerbationAdult Asthma ManagementAsthma Severity AssessmentAsthma Severity ClassificationController MedicationsPsychological Symptom BurdenPulmonary ExacerbationsSevere Asthma Exacerbation
Despite the use of effective medications to control asthma, severe exacerbations in asthma are still a major health risk and require urgent action on the part of the patient and physician to prevent serious outcomes such as hospitalisation or death. Moreover, severe exacerbations are associated with substantial healthcare costs and psychological burden, including anxiety and fear for patients and their families. The European Academy of Allergy and Clinical Immunology (EAACI) and the European Respiratory Society (ERS) set up a task force to search for a clear definition of severe exacerbations, and to also define research questions and priorities. The statement includes comments from patients who were members of the task force.
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Mepolizumab Treatment in Patients with Severe Eosinophilic Asthma
Héctor Ortega, Mark C. Liu, Ian Pavord et al. · New England Journal of Medicine · 2014 · 2.3K citations · Full text