<i>ZNNT1</i> long noncoding RNA induces autophagy to inhibit tumorigenesis of uveal melanoma by regulating key autophagy gene expression

Abstract

ADCD: autophagy dependent cell death; <i>ANXA2R</i>: annexin A2 receptor; <i>ATG12</i>: autophagy- related 12; <i>ATG5</i>: autophagy -related 5; ceRNA: competing endogenous RNAs; CQ: chloroquine; iTRAQ: isobaric tags for relative and absolute quantitation; lncRNA: long noncoding RNA; MAP1LC3/LC3: microtubule-associated protein 1 light chain 3; MTOR: mechanistic target of rapamycin kinase; MTORC1: MTOR complex 1; MTORC2: MTOR cmplex 2; PP242: Torkinib; RACE: rapid amplification of cDNA ends; <i>SQSTM1</i>/p62: sequestosome 1; UM: uveal melanoma.